2022-12-17
乔永康 生物科技研究中心特聘副研究员
Email: ykqiao@bnu.edu.cn
基本情况
2018年博士毕业于新加坡国立大学，先后在新加坡国立大学（2008年5月至2014年6月）和深圳华大生命科学研究院（2019年4月至2022年10月）从事助理研究员、博士后研究工作。2022年12月起就职于北京师范大学珠海校区自然科学高等研究院，担任特聘副研究员。
研究领域
研究领域聚焦肿瘤和呼吸系统疾病，旨在揭示疾病新型诊疗靶分子及其作用机制，同时开展相关药理学研究。主要研究内容包括：（1）肿瘤微生物定植并参与肿瘤发生发展的机制研究；（2）气道结构细胞参与呼吸系统疾病发生发展的细胞学研究；（3）肿瘤和呼吸系统疾病新型药物筛选；（4）疾病动物模型研究。
学习经历
2014.08-2018.12：新加坡国立大学，杨潞龄医学院生理学系，博士
2007.10-2008.03：新加坡国立大学，理学院，国际交换生（Attachment Student）
2006.09-2008.06：华中师范大学，生物化学与分子生物学，硕士
2002.09-2006.06：华中师范大学，生物科学，学士
代表著作
Tran T, Qiao Y, You H, Cheong DHJ. Emerging Roles of Nutraceuticals and Functional Foods in Immune Support: Immunity and Inflammation in Health and Disease. Chapter 25; edited by Chatterjee S and Bagchi D. Amsterdam. Netherlands: Elsevier 2018
代表论文
Tan Y#, Zhou H#, Lin Y#, Yi L#, Chen Z, Cao Q, Guo Y, Wang Z, Chen S, Li Y, Wang D, Qiao Y*, Yan Y*, FGF2 is overexpressed in asthma and promotes airway inflammation through FGFR/MAPK/NF-κB pathway in airway epithelial cells. Mil Med Res 2022, 9(1):7.
Tan Y#, Qiao Y#, Chen Z, Liu J, Guo Y, Tran T, Tan KS, Wang DY, Yan Y. FGF2, an immunomodulatory factor in asthma and chronic obstructive pulmonary disease (COPD). Front Cell Dev Biol 2020, 8:223.
Qiao Y#, Yan Y#, Tan KS#, Tan SSL#, Seet JE, Arumugam TV, Chow VT, Wang DY*, Tran T*. CD151, a novel host factor of nuclear export signaling in influenza virus infection. J Allergy Clin Immunol 2018, 141(5):1799-1817.
Qiao Y, Tam JK, Tan SS, Tai YK, Chin CY, Stewart AG, Ashman L, Sekiguchi K, Langenbach SY, Stelmack G, Halayko AJ, Tran T*. CD151, a laminin receptor showing increased expression in asthmatic patients, contributes to airway hyperresponsiveness through calcium signaling. J Allergy Clin Immunol 2017, 139(1):82-92.e5.
Hong H#, Chen F#, Qiao Y#, Yan Y, Zhang R, Zhu Z, Li H, Fan Y*, Xu G*. GSK-3β activation index is a potential indicator for recurrent inflammation of chronic rhinosinusitis without nasal polyps. J Cell Mol Med 2017, 21(12):3633-3640.
Tran T*#, Teoh CM#, Tam JK, Qiao Y, Chin CY, Chong OK, Stewart AG, Harris T, Wong WS, Guan SP, Leung BP, Gerthoffer WT, Unruh H, Halayko AJ. Laminin drives survival signals to promote a contractile smooth muscle phenotype and airway hyperreactivity. FASEB J 2013, 27(10):3991-4003.
主持、参与的科研项目
国家自然科学基金青年基金项目，牙龈卟啉单胞菌激活β1 integrin/CD151信号轴在食管鳞癌转移中的作用及其分子机制研究，2021-01至2023-12，主持。
中国博士后科学基金面上项目（一等资助），食管鳞癌菌群结构对化疗应答的影响及其作用机制研究，2019-07至2022-07，主持。
NMRC-IRG（新加坡），Role of CD151 in the modulation of airway smooth muscle contraction，2009-2012，参与。
MOE Tier 2（新加坡），Role of CD151 in influenza A virus infection in vitro and in vivo ，2016-2019，参与。
MOE Tier 1（新加坡），Assessment of the anti-remodelling potential of artesuante, an anti-malarial drug, in a chronic mouse asthma model，2015-2018，参与。
获奖情况
广东省海外青年博士后引进计划（2019）；
深圳市高层次人才C类、盐田区梧桐人才C类（2019）；
新加坡国立大学The Swee Liew-Wadsworth Research Publication Awards - Gold Research Award（2019 & 2018）；
新加坡国立大学Best Graduate Research Publication Awards（2018 & 2017）；
新加坡药理学会Winner of the Best Oral Presentation（2017）
湖北省优秀硕士学位论文（2009）
学术兼职
Military Medical Research 期刊科学编辑
学会会员: 新加坡药理学学会（Pharmacological Society of Singapore, PSS)、欧洲过敏与临床免疫学学会（European Academy of Allergy & Clinical Immunology, EAACI）
国际杂志审稿人：Frontiers of Medicine、Journal of Cellular and Molecular Medicine、Inflammation、Pulmonary Pharmacology & Therapeutics等
学术交流
Qiao Y and Tran T*. CD151, a novel target to modulate airway smooth muscle contraction and airway hyperresponsiveness in asthma. The Muscle Biology in Health & Disease conference. 1-2 Mar 2018, Singapore,
Qiao Y#, Yan Y#, Tan KS#, Tan SSL#, Chow VKT, Wang DY*, Tran T*. CD151 as a novel host factor to mediate influenza A virus viral nuclear export and modulate innate immunity in vivo and in vitro. The 9th Models of Disease and Physiology Symposium. 19 - 20th Sep 2017, Singapore
Qiao Y, Yan Y, Tan KS, Chow VT, Wang DY*, Tran T*. Targeting CD151 reduces severity of influenza a virus infection by promoting innate immune system and interrupting viral proteins nuclear export. Section: Infection and allergy. (Abstract published in Allergy Volume 72, Supplement S103), EAACI 2017 Congress, 21-24th June, 2017, Helsinki, Finland.
Qiao Y, Tran T*. CD151 as a determinant factor for airway hyperresponsiveness in asthma. 2nd Graduate Academic Progress in Pharmacology (GAPP) Meeting, Feb 22nd 2017, Singapore.
Qiao Y, Yan Y, Tan KS, Tan SSL, Seet JE, Chow VT, Wang DY*, Tran T*. CD151, a novel regulator of nuclear export singling in influenza virus infection in vitro and in vivo. Nature Conference on Viral Infection and Immune Response, Oct 21-24th, 2016, Wuhan PR China.
Tran T*, Qiao Y, Tam KC, Tai YK, Tan S, Chin CY, Stelmack G, Halayko AJ. The Tetraspanin, CD151: A New Mechanism For Regulating Airway Smooth Muscle Contraction And Airway Responsiveness. (Abstract published in Am J Respir Crit Care Med 2014.189:A5607), American Thoracic Society (ATS) International Conference, May 16-21st, 2014, San Diego, USA.
The 1st International Conference on Bioinformatics and Biomedical Engineering Wuhan, P.R. China, June 6-8th, 2007 (Oral presentation)
Proceedings of The Preventive Medicine Conference on Air Pollution and Health Research Wenzhou, P.R. China, Dec 4-8th, 2005 (Oral presentation)
